Endocrine Abstracts

Introduction: Autosomal dominant hypocalcemia (ADH) type 1 is a rare form of hypoparathyroidism, caused by heterozygous, inherited or de novo, activating mutations in the CASR. CASR is also expressed in the kidney and activating mutations lead to decreased calcium renal absorption. Activating mutations in the CasR, inhibits salt transport, leading to Bartteŕs syndrome (BS) type V which can co-exist with ADH1. Chronic myeloid leukemia (Cml) is characterized by the...

Introduction: Traditionally, obesity is thought to exert a positive impact on bone mineral density (BMD). However, the effect of adipose tissue on bone health is under investigation. Trabecular bone score (TBS) is a measure of bone texture, providing information on bone quality and microarchitecture, independently of BMD. Lower values of TBS indicate a worsening in bone quality and amplify fracture risk. Herein, we aimed to investigate the association of body composition and b...